Fine needle aspiration cytology of chondroblastoma of bone. Therapy for chondroblastoma consists primarily of surgical curettage. Smears characteristically revealed chondroblasts and osteoclastlike giant cells. Webpathology is a free educational resource with 10236 high quality pathology images of benign and malignant neoplasms and related entities. Cases of chondroblastoma have also been reported in the pelvis, femur, calcaneus, talus, scapula, patella, radius, metatarsals, skull, and fibula. To prevent recurrence, complete curettage is important. Chondromyxoid fibroma presents as a bigger, lucent, loculated lesion with a sharp sclerotic margin in the metaphysis of long bones. Local recurrence after such therapy occurs in approximately 15% of cases, 171, 173, 174 with time to recurrence ranging from 5 months to 8 years. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Chondroblastoma danafarberboston childrens cancer and.
The most frequently involved body regions are the hip, knee, and shoulder. It is generally regarded as a benign neoplasm, but sometimes it grows aggressively or recurs. This report documents the cytological features of two cases of chondroblastomas diagnosed by cytology. Both radiologic and histologic appearances of chondroblastomas of the patella are indistinguishable from those of chondroblastomas arising in other sites. It is thought to arise from an outgrowth of immature cartilage cells chondroblasts from secondary ossification centers, originating from the epiphyseal plate or some remnant of it. Cartilage plays an important role in the growth process. Chondroblastoma genetic and rare diseases information. Chondroblastoma benign definition of chondroblastoma. From january 1987 through december 1992, 22 patients with histologically confirmed chondroblastoma and prior mr imaging examinations were seen.
Chondroblastoma definition of chondroblastoma by medical. Chondroblastoma is a relatively rare, benign cartilaginous tumor, accounting for approximately 1% of the benign tumors of bone. Only rare cases have been reported in the diaphyseal region. It is more common in children and young adults affecting males more than females. Chondroblastoma pediatric orthopaedic society of north. In 1931, codman classified it as a chondromatous variant of giant cell tumors, when he described these lesions in the proximal humerus. The pain is often mild and progressive, and can sometimes be confused with minor trauma occurring in the past. We report a 28 yearold adult male who presented with a large swelling over the left shoulder region. Mar 17, 2004 chondroblastomas are rare epiphyseal bone tumors. A metaphyseal periosteal reactionoccurs in 1530% ofchondroblastomas. H3f3 mutation status of giant cell tumors of the bone. A mandibular flat myalgic splint was constructed for night time wear to reduce any stress which might be produced by nighttime clenching andor bruxing. Most often, the tumors develop at the ends of the femur thighbone, tibia shinbone, or humerus upper arm bone.
Preoperative imaging revealed a large tumor arising from upper end of humerus with extensive soft tissue involvement necessitating a forequarter. Although usually benign, chondroblastoma metastasizes on rare occasions, with fatal results. Older age of presentation for skull lesions is reported. Chondroblastoma is a rare primary bone tumor of young people. Access your health information from any device with myhealth. If you have problems viewing pdf files, download the latest version of adobe reader. Diagnostic challenge for the cytopathologist article pdf available in bmj case reports 2014may29 1 may 2014 with 78 reads how we measure reads. A reasonable differential diagnosis, including chondromalacia patella, is. Fluidfluid levels areoccasionally seen on images ofchondroblastomas, can simulate aneurysmal bonecysts. Chondroblastoma of bone is a rare lesion, and few large series have been reported. Ct guided radiofrequency ablation minimally invasive approach may be indicated for selected small tumors. Fine needle aspiration cytology of chondroblastoma of the fibula article pdf available in journal of cytology 314.
Pdf chondroblastoma is a rare, giant cellrich, benign neoplasm of bone. The size of the eradicated tumor cavity and the pathology differ so greatly from patient to patient that. There are many different types of cartilage in the body. Distinguishing between a chondroblastoma and an epiphyseal clear cell chondrosarcoma can be difficult. Fine needle aspiration cytological study of bone tumors. The official designation of a primary bone tumor as a chondroblastoma depends on the histologic finding of foci of chondroid matrix, andor ch. Chondroblastoma is a rare, benign, locally aggressive bone tumor that typically affects the epiphyses or apophyses of long bones.
Giant cell tumors of the bone and chondroblastomas are tumors of. Pdf fine needle aspiration cytology of chondroblastoma. Chondroblastoma of squamous part of the temporoparietal region. Fine needle aspiration cytology of chondroblastoma. Jun 27, 20 chondroblastoma is a benign bone tumor with a relatively high incidence in older children and adolescents during the period of active epiphyseal growth.
Chondroblastoma and chondromyxoid fibroma are benign but locally aggressive bone tumors. Chondroblastomas, also referred as codman tumors, are rare benign cartilaginous neoplasms that characteristically arise in the epiphysis or apophysis of a long bone in young patients. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. In this report, we describe the first case of chondroblastoma of the clivus presenting with cranial neuropathy that was treated with endoscopic endonasal resection. It most often affects the ends of the long bones, near the growth plate, in the arms at the shoulder, and in the legs at the hip and knee. In patients who are skeletally immature still growing there is always a risk of growth plate failure from the chondroblastoma since it usually grows adjacent to the growth plate and may damage it.
The cytologic diagnosis of chondroblastoma was confirmed on. The overall findings indicated benign chondroblastoma of the mandibular condyle. A subtle, solid, adjacentmetaphyseal periosteal reaction ispresent medially. Chondroblastoma is an uncommon, benign, cartilaginous neoplasm originating in an epiphysis or apophysis of a long tubular bone. The purpose of this paper is to report fortyseven cases treated by one group of surgeons and to identify factors. Since the past few decades fine needle aspiration cytology fnac. Chondroblastoma is a rare benign cartilaginous neoplasm that considered for approximately 1% of all bone tumors and characteristically emerges in the epiphysis of a long bone, especially the hummeros, femurand tibia. Pdf aggressive scapular chondroblastoma with secondary. Chondroblastoma and chondromyxoid fibroma abstract chondroblastoma and chondromyxoid. At cytology, other giant cellrich tumors and tumorlike lesions such as aneurysmal bone cyst abc, giant cell tumor, and chondromyxoid fibroma fall under the.
To define the characteristics of chondroblastoma at magnetic resonance mr imaging and the combination of findings that are diagnostic for chondroblastoma. Chondroblastoma is a rare type of benign noncancerous tumor that grows at the ends of the bodys long bones, close to the joints. The most common presentation of chondroblastoma is localized pain. Chondroblastoma journal of the belgian society of radiology. Chondroblastoma vs clear cell chondrosarcoma radiology. Nov 18, 20 chondroblastoma is a rare benign bone tumor of chondroblast origin that almost always occurs in a primary or secondary site of ossification, suggesting possible derivation from cartilage growth plates. Chondroblastoma is a rare type of noncancerous bone tumor that starts from cartilage. On fna, chondroblastoma had three dominant cytologic.
Osteoid osteoma, osteoblastoma, chondroblastoma, and giant cell tumor may manifest with pain. A chondroblastoma is a rare type of noncancerous bone tumor that begins in cartilage. Dec 03, 2018 a chondroblastoma is a rare, usually benign, tumor of bone that accounts for approximately 1% of all bone tumors. Chondroblastoma is a rare neoplasm accounting for less than 1% of all bone tumors. Age of occurrence is usually between 10 and 25 years with a male predominance.
Cartilage is the specialized, gristly connective tissue that is present in adults and the tissue from which most bones develop. After the surgery, the patient was given muscle strengthening exercises. Sometimes called codmans tumor, a chondroblastoma is a rare type of benign bone tumor that originates from cartilage. Very few cases with extracortical aggressive soft tissue invasion or metastasis are reported. Fine needle aspiration cytological study of bone tumors and. All site content, except where otherwise noted, is licensed under a creative commons attributionnoncommercialshare alike 3. This is the tough, rubbery connective tissue from which most bones develop. Helpful features which suggest a clear cell chondrosarcoma include. Fine needle aspiration cytology fnac is a minimally invasive and highly effective primary diagnostic method adopted worldwide to establish diagnosis. Chondroblastoma, a destructive lesion with a thin radiodense border, is usually seen in the epiphysis of long bones. We report a case of diaphyseal one in a years old girl that admitted. Fine needle aspiration cytological study of bone tumors and tumor like lesions with.
Chondroblastoma is uncommon, representing jess than i % of all bone tumors and approximately 3% of all benign bone tumors in the mayo clinic files. For language access assistance, contact the ncats public information officer. Continue reading to learn more about chondroblastoma or visit the bone and soft tissue tumor program page to learn about our expertise and treatment options for this condition. Benign bone tumor an overview sciencedirect topics. You can message your clinic, view lab results, schedule an appointment, and pay your bill. It was originally described by ewing in 1928 as a calcifying giant cell tumor. Chondroblastoma of the craniofacial skeleton is extremely rare, with most cases occurring in the squamosal portion of the temporal bone. Chondroblastoma of the distal femur resected through a small. Despite being rare, they are one of the most frequently encountered benign epiphyseal neoplasms in skeletally immature patients. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Chondroblastoma cbt is a rare, cartilageproducing bone tumor that tends to occur in the long bones of skeletally immature individuals.